A second goal of the Center is to investigate novel methods for stem cell growth, differentiation, sorting and delivery, using high throughput methods, novel assays, and innovative instruments for future applications of stem cel therapies.
Faculty Research
Rick Dahlquist
Chemistry & Biochemistry
Protein structure and function.
Andrew Cleland
Physics
Nanomechanical and nanoelectronic devices; electronic biosensing of cells and molecules.
Frank Doyle
Chemical Engineering
Systems biology; biosystems analysis and control; biomedical control systems; nonlinear model-based control.
Craig Hawker
Chemistry & Biochemistry
Design, synthesis and exploitation of nanoscopically defined materials and microelectronic devices; hydrogel-based cell scaffolds for hESC differentiation.
Patrick Daugherty
Chemical Engineering
Engineering of protein-ligand interactions; microfluidic cell sorting; intercellular screens for protein-protein interactions.
Carl Meinhart
Mechanical Engineering
Development and analysis of MEMS-based micro-fluidic devices; optical instrumentation for micro-scale fluid mechanics; wall turbulence.
Igor Mezic
Mechanical Engineering
Research Description: Operator-theoretic approach to analysis of nonlinear dynamical systems, applications in microfluidics and (bio)-nanotechnology.
Erkki Ruoslahti
Burnham Institute
Cell adhesion and tumor metastasis; tissue-specific vascular "zip codes" for delivery of nanoparticles to specific tissue targets; novel synthetic matrices to support hESC survival, proliferation, and delivery to specific niches.
Tom Soh
Mechanical Engineering
High throughput cell screening, including novel methods for sorting hESC derivatives; molecular screening and directed evolution; integrated biosensors.
Galen Stucky
Materials
Synthesis of mesoporous materials and their applications, specifically the interface of inorganics with biomolecules and novel materials for propagation and delivery of hESCs and hESC derivatives.
Megan Valentine
Mechanical Engineering
Nanoscale manipulation and measurement techniques to probe biological materials from single proteins to entire cells; mechanical properties of the cytoskeleton.