News & Media

Lab Specific Gene Expression Signatures in Pluripotent Stem Cells

August 06, 2010

James D. Cooper, Associate Professor in the Molecular Cellular and Developmental Biology Department as well as the Biomolecular Science and Engineering Program at UC Santa Barbara was published in the August issue of Cell Stem Cell for his collaborative work with Aaron M. Newman using an unsupervised clustering algorithm called AutoSOME to study lab specific gene expression signatures in Human Induced Pluripotent Stem Cells(iPSC) and Human Embryonic Stem Cells(hESC). Reanalysis of microarray gene expression data from seven different laboratories shows strong correlation between gene expression signatures and specific laboratories in both ESC and iPSC lines.

Cell Stem Cell August 2010

Guggenheim Fellowship awarded to Co-Director Soh

April 23, 2010

Hyongsok (Tom) Soh, Co-Director of UCSB’s Center for Stem Cell Biology and Engineering, has been awarded a 2010 Guggenheim Fellowship to pursue his research combining microfluidics and high-throughput sequencing to accelerate development of aptamer reagents that bind protein targets.

UCSB Engineering

UCSB, UCL Scientists Rescue Visual Function in Rats Using Induced Pluripotent Stem Cells

December 03, 2009

Two studies recently published describe the derivation and functional testing of retinal pigmented epithelium (RPE) from induced pluripotent stem cells (iPSC’s). Lead by MCDB professor and CSCBE executive director Dennis Clegg in collaboration with Pete Coffey from the University College London, these studies show that RPE can be derived from iPSC’s and can rescue visual function in a rat model of blindness. These results provide the potential for cell replacement therapy for age-related macular degeneration. The research was published in the October 27th, 2009 issue of the journal Stem Cells and on December 2nd, 2009 in the online open-access journal PLoS One.

UCSB Press Release

UCSB and Other Institutions Receive $20 Million for Vision Research Using Stem Cells

October 28, 2009

The California Institute for Regenerative Medicine (CIRM) and UK Medical Research Council (MRC) are funding a $20 million multi-institutional grant on vision research. UC Santa Barbara will receive $2.5 million for their stem cell-related research. This funding will help translate basic stem cell research to clinical trials on treating macular degeneration.

UCSB Press ReleaseCIRM Press ReleaseMacular Degeneration Video

Hyongsok (Tom) Soh Research Receives NIH Director’s Award

September 24, 2009

UC Santa Barbara stem cell researcher Prof. Hyongsok (Tom) Soh has receives the National Institutes of Health (NIH) Director’s Transformative R01 Award. These awards are given to fund exceptionally innovative, original research projects that can significantly affect a broad biomedical research area. Prof. Soh was awarded for his research on a novel, high throughput cell sorting technology, developed by his laboratory, that has extensive applications for stem cell research and proteomics research.

NIH Press Release

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